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Growth · Software Engineer Interview Guide

Applies via Ashby

How to Pass the Owkin Software Engineer Interview in 2026

The Owkin DNA (TL;DR)

Owkin seeks candidates demonstrating strong scientific acumen, technical expertise in AI/ML, and a passion for applying these to biomedical challenges. They value problem-solving skills, collaborative potential, and the ability to navigate complex, data-rich environments in drug discovery.

The Owkin Interview Loop

Your onsite loop will typically consist of 5 rounds.

  1. 1

    Round 1

    Recruiter Screen
    Motivation, role fit, logistics.
  2. 2

    Round 2

    Coding Screen
    LeetCode-medium algorithmic problems under time pressure.
  3. 3

    Round 3

    System Design
    Distributed systems, trade-offs at scale, architecture under constraints.
  4. 4

    Round 4

    Onsite Coding
    LeetCode-hard, debugging, code clarity, edge cases.
  5. 5

    Round 5

    Behavioral / Leadership
    Past evidence of ownership, influence, resolving conflict.

The Danger Zone: Top Reasons Candidates Fail

Based on our database of Owkin interview outcomes, avoid these common traps:

  • Introducing premature optimization that harms readability.
  • Making assumptions about the root cause without systematic investigation.
  • Not demonstrating a willingness to compromise or find common ground.
  • Inefficient brute-force comparison of all sequences.

Test Yourself: Real Owkin Questions

Three real prompts pulled from our database.

Type · Data Structures

Implement a data structure that can store and query patient cohorts based on multiple criteria (e.g., age range, specific diagnosis codes, medication history). Queries should be efficient, especially when combining multiple criteria.

Type · Conflict Resolution

Tell me about a time you had a significant disagreement with a colleague or manager. How did you approach the situation, and what was the resolution?

Type · Algorithmic

Given a dataset of patient genomic sequences and corresponding treatment outcomes, design an algorithm to efficiently find sequences that are highly correlated with a positive treatment response. Assume sequences can be very long and the dataset is large.

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Owkin Interview Question Bank

A sample from our database, grouped by round. Sign up to see the full set.

9 of 17 questions shown

1

Recruiter Screen

1
  1. 1

    Type · Motivation

    Why are you interested in working at Owkin, specifically within the pharma and healthcare AI space?
2

Coding Screen

3
  1. 2

    Type · Algorithmic

    Given a dataset of patient genomic sequences and corresponding treatment outcomes, design an algorithm to efficiently find sequences that are highly correlated with a positive treatment response. Assume sequences can be very long and the dataset is large.
  2. 3

    Type · Algorithmic

    You have a stream of anonymized patient data points (e.g., lab results, medication adherence) arriving in real-time. Design a system to detect anomalous patterns that might indicate a rare adverse drug reaction. You need to maintain a rolling window of recent data.
  3. + 1 more questions in this round (sign up to unlock)
3

System Design

3
  1. 4

    Type · Distributed Systems

    Design a federated learning system for Owkin. Consider how multiple hospitals can train a shared AI model on their local patient data without sharing the raw data itself. Focus on the data flow, model aggregation, and security aspects.
  2. 5

    Type · Architecture

    Owkin is building a platform to connect researchers with curated datasets for drug discovery. Design the backend architecture for this platform. Consider data ingestion, storage, search capabilities, and access control for sensitive research data.
  3. + 1 more questions in this round (sign up to unlock)
4

Onsite Coding

3
  1. 6

    Type · Algorithmic

    Given a list of clinical trials, each with a start date, end date, and a list of associated patient IDs, write a function to find all patients who were participating in *any* overlapping trials. A patient can be in multiple trials simultaneously.
  2. 7

    Type · Debugging

    A data pipeline processing patient EHR data is intermittently failing with cryptic errors related to data type mismatches or missing values. The pipeline uses several stages (ingestion, cleaning, feature extraction, model training). How would you approach debugging this? Provide specific steps and tools you might use.
  3. + 1 more questions in this round (sign up to unlock)
5

Behavioral / Leadership

7
  1. 8

    Type · Conflict Resolution

    Tell me about a time you had a significant disagreement with an engineer or a scientist regarding a product decision. How did you approach it, and what was the outcome?
  2. 9

    Type · Conflict Resolution

    Tell me about a time you had a significant disagreement with a colleague or stakeholder regarding a technical decision or project direction. How did you approach the situation, and what was the outcome?
  3. + 5 more questions in this round (sign up to unlock)

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Interview tracks at Owkin

How Owkin's DNA translates across functions. Pick your role.

SWEs are assessed on their ability to build scalable, secure, and robust platforms for AI/ML in a regulated healthcare context. Expect deep dives into distributed systems, MLOps, data privacy, and strong coding skills, particularly for infrastructure supporting federated learning or biomarker development.

Data Structures

Implement a data structure that can store and query patient cohorts based on multiple criteria (e.g., age range, specific diagnosis codes, medication history). Queries should be efficient, especially when combining multiple criteria.

Conflict Resolution

Tell me about a time you had a significant disagreement with a colleague or manager. How did you approach the situation, and what was the resolution?

+ 1 more

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Compare Owkin with similar employers

Same DNA, different bar. Browse the closest companies in our database and see how their loops differ.

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